ABSTRACT
The Defined Animal Model ...........................................................................................................864 Renal Impairement and Genobiotic Metabolism and Toxicity ...........................................864 Hepatic Impairment: Xenobiotic Metabolism and Toxicity ................................................868 Impaired GI Absorption .......................................................................................................873 Pregnancy .............................................................................................................................875 Influence of Gender on Xenobiotic Absorption, Disposition, and Toxicity .......................878 Microbiological Definition ...................................................................................................885 Genetic Definition ................................................................................................................886 Environmental And Nutritional Condition...........................................................................890 Susceptibility Factors ...........................................................................................................890 Summary...............................................................................................................................890
Species Peculiarities.......................................................................................................................891 Species Variation ..................................................................................................................891
