ABSTRACT
Protein 1 ............................................................................................ 118 9.4 Aftermath ..................................................................................................... 119
9.4.1 PrPc Interaction with STI1 Triggers Neuroprotection ...................... 119 9.4.2 PrPc Interaction with Laminin and Vitronectin and
Validation of Complementary Hydropathy Theory .......................... 121 9.5 Conclusions ................................................................................................... 125 Acknowledgments .................................................................................................. 125 References .............................................................................................................. 125
Protein-protein interactions are major pillars of life on this planet. Although much has been devoted to their study in the last century, we still have many unanswered questions. How did protein-protein interactions arise? What are the evolutionary mechanisms responsible for the emergence of protein interacting pairs? How did the protein interaction network that sustains most of life’s physiological aspects come to exist?
