ABSTRACT

How many biochemical pathways triggering cell death forms are available to

normal, preneoplastic, and neoplastic cells? What morphological and biochem-

ical alterations result from each of these pathways? Which ones predominate in

each type of neoplasm? Which may be triggered therapeutically, and what is the

best approach to triggering these cell death pathways? What are the inhibitors

and activators of each of these pathways?