ABSTRACT
A novel technology to prepare modified reverse microemulsion (denoted NSSL, nanosized self-assembled liquid) vehicles loaded with cosmetoceuticals, based on permitted ingredients that can be progressively diluted with water, was developed recently in our labs. The microemulsion isotropic regions representing water-in-oil (W/O), bicontinuous mesophase, and oil-in-water (O/W) microemulsion structures are presented in a phase diagram so-called U-type. In such compositions in the isotropic regions of the phase diagram, structures can invert from L2 (reverse micelles) to an L1 (direct micelles) phase via W/O, bicontinuous, and O/W regions progressively, without phase separation.
