chapter  50
Pathophysiology of Arterial Thrombosis
Pages 10

Atherosclerosis is the most common cause of major disability and death in the United States. The most devastating complication of this disease occurs when a platelet-rich thrombus abruptly occludes arterial blood flow resulting in acute myocardial infarction (MI), stroke, or sudden cardiac death (SCD). Each year, 1.1 million Americans suffer from MI and 700,000 Americans suffer from a new or recurrent stroke.This chapter reviews the basic pathophysiology of arterial thrombosis.