ABSTRACT
I. Introduction................................................................................. 177 II. Electrophysiological Characteristics of Native GnRH
Neurons ....................................................................................... 178 A. Initial Studies......................................................................... 178 B. Basic Membrane Properties of GnRH Neurons
in the Mouse .......................................................................... 179 C. Ligand-Gated Receptors Expressed by GnRH
Neurons in the Postnatal Mouse.......................................... 181 III. Direct Gonadal Steroid Effects upon Native GnRH
Neurons?...................................................................................... 183 IV. Effects of Gonadal Steroids upon GnRH Neuron
Membrane Properties ................................................................. 184 V. Conclusions ................................................................................. 186
References ............................................................................................. 187
The biosynthetic and secretory activity of the mammalian gonadotropinreleasing hormone (GnRH) neurons is clearly regulated by the fluctuating levels of circulating estrogen and progesterone in the female.