ABSTRACT
References..............................................................................................................334
All neuronal structures interact with their surroundings in one way or another. For example, single neurons send and receive synaptic signals, cortical networks communicate with other networks via a multitude of projections, spinal circuits send signals to muscles and receive sensory feedback, etc. In experimental setups, a neuron or a network may sometimes be studied in isolation but in general the
environment must also be taken into account to establish the right conditions for normal operation. When experiments are done
in vitro
, this normally implies that the neuron or network is deprived of the natural input and output and, thus, works in isolation.