ABSTRACT

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The administration of drugs to the gastrointestinal tract (GIT) normally involves an imme-

diate release formulation, typically a tablet or a capsule. Although such formulations are

still preferred for their relative simplicity and low cost, formulations that address specific

issues in oral drug delivery require more sophisticated attributes. Extended release dosage

forms are now used in a number of products. These products permit reduced dosing fre-

quency, leading to improved patient compliance and, in some instances, improved pharma-

cologic response.