ABSTRACT
External Genitalia Development: A Model for Organogenesis? .....................265 Emergence of Growth Factors: Fibroblast Growth Factors (FGFs) as a
Beginning of Growth Factor Analysis of External Genitalia Formation ....269 Implications for Understanding Human Birth Defects Based on
Molecular Embryology for External Genitalia Development .....................270 Role of Fgf10 During External Genitalia Formation: The First Case of
Gene Knock-Out Mouse Model for External Genitalia Development .......270 Identification of an Essential Epithelial Gene: The Role of Shh in
Urethral Plate Epithelia v.s. Mesenchymal Fgf10.......................................271 Genes Necessary for Setting Initial Developmental Field: Genetic Cascades
Necessary for External Genitalia Outgrowth Induction ..............................271 The Role of Developing Epithelia in Epithelial-Mesenchymal Interaction:
The Development of External Genitalia and Embryonic Gut.....................272 Role of Bone Morphogenetic Protein (Bmp) Genes in External
Genitalia Development.................................................................................273 Do Signaling Epithelia Explain All Aspects of External
Genitalia Development? The Role of DUE.................................................274 Acknowledgment...............................................................................................274 References .........................................................................................................275
