ABSTRACT
I. Introduction .............................................................................................................................97 II. ANCA Terminology................................................................................................................97 III. ANCA-Related Antigens and Testing Methodology..............................................................99 IV. Diseases Associated with ANCA..........................................................................................100 V. The Usefulness of ANCA for Clinical Practice and Predictive Value ................................101 VI. The Potential Pathogenetic Role of ANCA..........................................................................102 VII. Conclusions ...........................................................................................................................103 References ......................................................................................................................................104
Antibodies against neutrophils were described as early as 1974 in patients with rheumatoid arthritis
and shortly thereafter in patients with renal disease.
