ABSTRACT

I. The GABA Receptors ...........................................................................................................153 II. Neuroanatomical Considerations ..........................................................................................153 III. Pathophysiology of GABA in Schizophrenia.......................................................................154 IV. Putative Mechanisms of Action............................................................................................155 V. Clinical Trials of GABAergic Agents ..................................................................................155 VI. Benzodiazepines....................................................................................................................156 VII. Valproate................................................................................................................................156 VIII. Clinical and Research Implications ......................................................................................158 References ......................................................................................................................................159