ABSTRACT

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327 Human Immune System Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328 Animal Immune System Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 Immune Function Assays Used in Developmental Immunotoxicity Testing . . . . . 334 Immunosuppression in Rodents Perinatally Exposed to Immunotoxic Agents . . . 335 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339

Disclaimer: This chapter has been reviewed by the Environmental Protection Agency’s Offi ce of Research and Development and approved for publication. Approval does not signify that the contents necessarily refl ect the views and policies of the Agency, nor does mention of trade names or commercial products constitute endorsement or recommendation of use.