ABSTRACT
Introduction ......................................................................................................... 111 Generic structure of neisserial LOS ................................................................. 112 Genetics of core biosynthesis............................................................................ 113 Genetics of
α
-chain biosynthesis...................................................................... 114 Genetics of high-frequency variation .............................................................. 116 Sialylation of LOS ............................................................................................... 118 Genetics of
β
-chain biosynthesis ...................................................................... 119 Genes with secondary effects on LOS biosynthesis...................................... 119 Biosynthetic genes not yet identified ..............................................................120 Selective advantage of LOS in pathogenesis .................................................120