ABSTRACT
Introduction to mycobacteria............................................................................207 Mycobacterial cell wall core.........................................................................208 Mycobacterial cell envelope carbohydrates...............................................208 Drug development is a major rationale for studying mycobacterial
cell surface carbohydrate biosynthesis ..................................................209 The genome of
M. tuberculosis
has been sequenced ................................209 Scope of the present review article .............................................................209
Structure, biosynthesis, and genetics of AG ..................................................210 Structure ..........................................................................................................210 Overall biosynthesis of AG ..........................................................................210 Sugar donor biosynthesis and genetics......................................................210 Biochemistry and genetics of the glycosyl transferases ..........................215
Conclusion ...........................................................................................................217 Acknowledgments ..............................................................................................218 References.............................................................................................................218
The genus