ABSTRACT
The study of learning has a rich tradition, going back at least to the days of Aristotle, who proposed that the formation of associations between coincident events is the way humans learn. More famously associated with learning, especially in the popular mind, is Pavlov who, in the 1920s, studied what is now known as classical conditioning or Pavlovian conditioning. In these well-known experiments, an unconditioned stimulus (food), which naturally causes an unconditioned reex (salivation), was presented along with a neutral stimulus (a bell) with enough repetition that, eventually, the bell began to evoke the salivation even without the presence of food (conditioned
Introduction ............................................................................................................ 125 The Importance of Neuronal Ensembles ............................................................... 127 Using Nonhuman Primates to Study Learning Using Chronic Recording
Methods ....................................................................................................... 127 Analysis of Single Unit Response Properties ........................................................ 130
Quantitative Analysis of Peri-Event Time Histograms .............................. 130 Distance Index (DI) Analysis ..................................................................... 133
Analysis of Neural Ensemble Data ........................................................................ 135 Using Articial Neural Networks (ANNs) for Single Trial
Classication Based on Neural Ensemble Recordings .................... 136 LVQ-Based Population Analyses ................................................................ 136 Quantication of Neuronal Responses with LVQ ...................................... 137 Population Distance Index (pDI) Analysis for Single Trial
Classication Based on Neural Ensemble Recordings .................... 137 Moving-Window Analysis .......................................................................... 139 Cross Correlations to Study Neuronal Interactions .................................... 139 Partial Directed Coherence (PDC) Analysis .............................................. 139 Principle Component Analysis (PCA) ........................................................ 140 Control Analyses ........................................................................................ 140
Conclusions ............................................................................................................ 141 References .............................................................................................................. 141
response). At that point the bell had become a conditioned stimulus, i.e., a stimulus that, after learning a new association, evokes the conditioned response.
