ABSTRACT

Physical examination should be performed on mice upon arrival at the facility and on mice exhibiting any abnormalities. With large groups of mice, a few representative individuals or any obviously abnormal animals should be examined. Findings should be recorded in a colony record or other appropriate health record. Physical examination of the mouse can be performed in the following manner:

1. General assessment of behavior of the animal within the cage and during removal from the cage. Findings such as lethargy or aggressiveness or hunched appearance should be noted.