ABSTRACT

Nonvesicular ................................................................................................136 6.4 Routes of Zinc Entry....................................................................................137 6.5 Intracellular Signaling Events Mediating Zinc Toxicity..............................138 6.6 An Effector Mechanism of Zinc Toxicity: Oxidative Stress........................139 6.7 Induction and Activation of NADPH Oxidase by Zinc................................141 6.8 Another Effector Mechanism of Zinc Toxicity: p75NTR/NADE-Mediated

Apoptosis ....................................................................................................141 6.9 Protective Measures Against Zinc Toxicity ................................................143 6.10 Summary ......................................................................................................144 6.11 Acknowledgment ........................................................................................145 References ............................................................................................................145