ABSTRACT
The family Loganiaceae consists of approximately 20 genera and 500 species of tropical trees, shrubs, and climbers that commonly produce iridoids and monoterpenoid indole alkaloids that are formed by the condensation of tryptamine and secologanin. An exciting reserve of potentially active Loganiaceae is in the medicinal plants of the Pacific Rim, where about 20 species are used to invigorate, to counteract putrefaction, to treat eye diseases, and to expel worms from the intestines. Example of medicinal Loganiaceae is Gelsemium nitidum, the roots of which are occasionally used to reduce headache. Fagraea auriculata Jack is a climber or small tree that grows from sea level to 1200m in Burma, Thailand, Cambodia, Laos, Vietnam, and throughout the Malay Archipelago. In Indonesia, the leaves are used to reduce fever and to ease headaches. In Indonesia, the leaves are used to reduce fever and to ease headaches. In the Solomon Islands, the bark is used externally to treat skin diseases.
