ABSTRACT

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Wounds originate from a variety of sources. Burns, surgery, infectious disease, trauma, radiation therapy, decubiti, and diabetic or vascular ulcers are only a few of the many causes of tissue destruction. Normal progression of tissue repair requires conditions that maximize vascular sufficiency, aseptic state, immunity, and nutritional balance. This chapter focuses on the metabolic alterations produced by burns and wounds, the nutritional components of tissue repair, methods for assessment of nutritional adequacy, and therapeutic modalities that maximize anabolism and thus the promotion of healing, despite wound etiology.