ABSTRACT

Introduction............................................................................................................261 Proteome Microarray Technology.............................................................261 Protein Microarray Fabrication and Assay Development.........................262 Quantitative Analysis on Protein Microarrays ..........................................264

Applications of Protein Microarrays in Drug Discovery .....................................265 Chemical Genetics .....................................................................................265 Small-Molecule Target Identification — A Bottleneck in the Practice of Chemical Genetics........................................................266 Proteome Microarrays as a Novel Target Identification Tool...................267

Limitations and Future Challenges .......................................................................269 References..............................................................................................................271