ABSTRACT
The measurement and detection of molecules and their interactions is the foundation of analytical
chemistry as applied to biomedical and environmental sciences. Traditionally, advances in instrumen-
tation and the development of novel detection modalities have resulted in the ability to monitor target
species and processes previously inaccessible, generating advances in all realms of science. For example,
the development of the portable electrochemical glucometer has improved the routine analysis of blood
glucose levels thereby improving the quality of life for millions of diabetics worldwide. Instrumental
advances in nuclear magnetic resonance (NMR) spectroscopy and imaging have enabled discoveries in
organic chemistry, molecular biology, and cognitive science. Advances in sensor technology are clearly
important not only in furthering fundamental biomedical research but also for their direct impact on
the general public.