chapter  13
16 Pages

Calpains in Normal and Aberrant Cell Physiology

Calpains constitute a family of calcium-dependent proteases showing ubiquitous distribution in a wide spectrum of animal species. They are intracellular cysteine proteases. They cleave substrate proteins in a manner that might constitute a mechanism of regulation of the protein substrates (Croall and De Martino, 1991; K. Suzuki

et al.