chapter  15
2 Pages

Parvalbumins in Neuronal Development, Differentiation, and Proliferation

The neuroepithelial ventricular zone of telencephalic ventricles gives rise to the majority of neurones and the glial component, which form the mammalian cerebral cortex. It has become increasingly obvious over the past few years that the various neuronal CBPs, such as calretinin, calbindin, neurocalcin, and parvalbumins, may each uniquely identify neuronal subpopulations across the cortical regions. Subpopulations with different CBPs may indeed represent metabolically distinctive cellular subtypes, and the presence of specific proteins may hold functional implications for the particular subtypes. These proteins may be playing different calcium-signalling roles in different cell types under different biological parameters.