ABSTRACT
Acknowledgments .......................................................................................................................... 90
References....................................................................................................................................... 90
The mouse was the first live animal to be imaged using magnetic resonance imaging (MRI) [1], but
it has not been utilized extensively in small animal imaging experiments. Historically, rats and
guinea pigs have been better studied due to their larger size. This allows for easier manipulation
and more signal available for imaging. However, because both the draft sequences of the human
and mouse genome have been completed in the last few years, the field of mouse MRI is rapidly
expanding as biologists need new tools to both discover models of human disease and to test
responses to different drug therapies administered to large numbers of mice.
