ABSTRACT

The process of discovering new drugs is positioned at the interface between academic, (i.e., basic

research into biological phenomena) and clinical research, defining the efficacy and safety of new

drug candidates. In this sense it belongs to the realm of goal-oriented, applied research, and its

benchmark is productivity in terms of number of novel, attractive, and technically feasible drug

candidates that can be offered to the disciplines of preclinical and clinical research and

development, and that have a reasonable chance of success.