ABSTRACT
The beginning of the 20th century coincided with a conceptual advancement that has guided most of the experimental research on the neurobiology of memory: the
hypothesis of memory consolidation. Georg Elias Müller and his pupil Alfons Pilzecker published an ample monograph in which they reported 40 experiments carried out between 1892 and 1900, with the aim of identifying laws that govern the establishment and retrieval of memory. They devised the concept of memory consolidation and introduced it into scientific literature. The major conclusions of their work were that memory fixation requires time (consolidation) and that memory is vulnerable during the period of consolidation.
