ABSTRACT

The term “genomics” has come to encompass a large number of disciplines including gene sequencing, analyses of gene expression at the level of the transcriptome, genetic variability, proteomics, and metabolomics. The wide array of information generated from the “-omics” has also resulted

in the development of complex analyses of these data, and consequently, the development of bioinformatics. Toxicologists quickly realized the immense potential of these emerging sciences for understanding complex biochemical pathways leading to pathological conditions. Hence, toxicogenomics, which refers to the effects of toxic chemicals on genome analysis, has become a flourishing area of toxicology, and represents an excellent field of research for the application of genomics technologies.