ABSTRACT

Introduction..................................................................................................................................157 Genomic and genetic features of

B. aphidicola

........................................................................158 Genome size reduction and chromosomal stasis .........................................................160 Increase in AT content ......................................................................................................161 Substitution rate acceleration ..........................................................................................162 Loss of codon bias and change in amino acid composition ......................................162 Plasmids of amino acid biosynthesis .............................................................................163

Genome reduction tempo and mode.......................................................................................164 Gene expression of a reduced metabolism.............................................................................165 Is