ABSTRACT

Most neurons have two distinct compartments. As described almost 100 years ago by Ramón Y Cajal,

the dendritic domain is composed of relatively short branches that gradually taper and form acute angles between sibling branches. In contrast, processes belonging to the axonal compartment travel for long distances with little

tapering and branches usually occur at right angles. Ultrastructurally, the most conspicuous difference is visible at synapses where dendrites are most commonly postsynaptic to presynaptic axonal specializations.