ABSTRACT
Activity in Neuronal Populations ....................................................................7 1.6 Why Is It So Hard to Test the Contribution of Neurons to Motor
Patterns and Behavior in Vertebrates? .............................................................8 1.7 Optical and Genetic Methods Offer a Potential Solution ...............................8 1.8 The Larval Zebrafish Model ............................................................................9 1.9 Imaging Neuronal Activity in Zebrafish..........................................................9 1.10 Cell-Specific Perturbation of Activity via Laser Ablation ............................12 1.11 Why Genetic Approaches Are Potentially Better than Those
Used So Far to Study Circuits in Zebrafish ..................................................13 1.12 Reverse Genetics in Zebrafish .......................................................................14 1.13 Genetic Perturbation of Activity....................................................................15 1.14 Optical and Genetic Approaches Are Possible in Mammals
as Well as Zebrafish .......................................................................................16 1.15 Summary and Conclusions ............................................................................17 References................................................................................................................17
This chapter deals with our understanding of the circuits for movement in spinal cord. The emphasis is on what is missing in our knowledge of spinal circuits. There are significant gaps in our understanding and it is helpful to consider why it is that
