ABSTRACT
Junction Proteins ............................................................................................21 2.4 Morphology of Tight Junctions in Freeze-Fracture Replicas and
Immunolocalization of Tight Junction Proteins in Tight Junction Strands .....23 2.5 Tight Junctions and Their Lipid Environment ..............................................26 2.6 Ultrastructure of Developing Epithelial Tight Junctions ..............................30 2.7 Structure-Function Correlations ....................................................................32 2.8 Summary ........................................................................................................32 References................................................................................................................33
Epithelia form vital cellular barriers that generate and maintain a very different fluid and solute composition between adjacent tissue compartments. This requires that epithelial cells be selectively permeable to molecules that are either secreted or absorbed, a process that is mediated by asymmetrically distributed cellular transport mechanisms via a route known as the
