ABSTRACT
Pain Models..................................................................................................115 5.3 Nicotinic Receptor Subtypes Involved in the Antinociceptive Effects
of Nicotine and Nicotinic Agonists .............................................................118 5.3.1 Supraspinal Sites ..............................................................................118 5.3.2 Spinal Sites.......................................................................................121 5.3.3 Peripheral Sites ................................................................................123
5.4 Factors Modifying Nicotinic Analgesia.......................................................126 5.4.1 Gender Studies .................................................................................126 5.4.2 Genetic Studies ................................................................................127
5.5 Human Studies .............................................................................................128 5.6 New Nicotinic Agonists as Analgesics ........................................................130
