ABSTRACT

Vasculitic Neuropathy Peripheral neuropathy is common in many systemic necrotizing vasculitides (SNV) (Table 6.1) and, thus, is an important clinical manifestation of SNV. When peripheral neuropathy is caused by necrotizing vasculitis, it is called vasculitic neuropathy. Peripheral neuropathy is due to ischemic damage of nerves as a result of occlusion of blood vessels associated with an inflammatory process in the vessel walls in the vasa nervorum. This can occur either as a manifestation of multisystem involvement in SNV or as an independent disease process such as nonsystemic vasculitic neuropathy. Although vasculitic neuropathy is relatively rare, recognizing it is important because it is potentially treatable.