chapter  2
24 Pages

Physicochemical Principles of MR Contrast Agents

Agents..........................................................................................................16 2.5 Paramagnetic Enhanced Nuclear Relaxation .........................................................................17 2.6 T2 Agents ...............................................................................................................................23 2.7 Imaging Physics: T

and T

Agents .......................................................................................25 2.8 PARACEST Agents ................................................................................................................28 2.9 Direct Observation of Nonhydrogen Nuclei..........................................................................31 2.10 Common Features and Concerns ...........................................................................................32 2.11 Conclusion ..............................................................................................................................32 References ........................................................................................................................................33

The magnetic resonance (MR) image in clinical and biological systems is typically an image of the hydrogen atoms in water and fat. Water hydrogen is chosen because it is very abundant; tissue is about 90