ABSTRACT

Corynebacterium glutamicum, like other organisms, must react to changes in its environment to ensure that nutrition sources will be utilized economically and that the cell will adapt to various conditions. To meet these demands, the cell is equipped with numerous types of control over its metabolic activities. The primary and major point of control of gene expression is transcription initiation, which represents the first step in the flow of genetic information. Since most examples of regulation of gene expression in C. glutamicum describe transcriptional control, the main focus of this chapter is this level of regulation.