ABSTRACT

Anatomically, the stomach can be divided into three major regions: fundus

(the most proximal), corpus, and antrum. The regions close to the esophagus

and duodenum are called cardias and pylorus, respectively. The main function

of the stomach is to process and transport food. After feeding, the contractile

activity of the stomach helps to mix, grind, and eventually evacuate small

portions of chyme into the small bowel, while the rest of the chyme is mixed

and ground. The stomach wall, like the wall of most other parts of the

digestive canal, consists of three layers: the mucosal (the innermost), the

muscularis, and the serosal (the outermost). The mucosal layer itself can be

divided into three layers: the mucosa (the epithelial lining of the gastric cavity),

the muscularis mucosae, and the submucosal layer (consisting of connective

tissue interlaced with plexi of the enteric nervous system). The second gastric

layer, the muscularis, can also be divided into three layers: the longitudinal

(the most superficial), the circular, and the oblique.