chapter  1
24 Pages

Nanotechnology.in.Stem.Cell.Biology.and.Technology

Nanotechnology.is.the.science.and.engineering.concerned.with.the.design,.synthesis,.characterization,.and.application.of.materials.and.devices. that.have.a.functional.organization. in.at. least.one. dimension.on.the.nanometer.(nm).scale,.ranging.from.a.few.to.about.100.nm..Nanotechnology.is. beginning.to.help.advance.the.equally.pioneering.field.of.stem-cell.research,.with.devices.that.can. precisely.control. stem.cells. (SCs).and.provide.nanoscaled-biodegradable.scaffolds.and.magnetic. tracking.systems..SCs.are.undifferentiated.cells.generally.characterized.by.their.functional.capacity. to.both.self-renew.and.to.generate.a.large.number.of.differentiated.progeny.cells..The.characteristics.of.SCs.indicate.that.these.cells,.in.addition.to.use.in.developmental.biology.studies,.have.the. potential.to.provide.an.unlimited.supply.of.different.cell.types.for.tissue.replacement,.drug.screening,.and.functional.genomics.applications..Tissue.engineering.at.the.nanoscale.level.is.a.potentially. useful.approach.to.develop.viable.substitutes,.which.can.restore,.maintain,.or.improve.the.function. of.human.tissue..Regenerating.tissue.can.be.achieved.by.using.nanobiomaterials.to.convey.signals. to.surrounding.tissues.to.recruit.cells. that.promote.inherent.regeneration.or.by.using.cells.and.a. nanobiomaterial.scaffold.to.act.as.a.framework.for.developing.tissue..In.this.regard,.nanomaterials.

1.1. Introduction.............................................................................................................................1 1.2. Stem.Cells.and.Types...............................................................................................................2