ABSTRACT

The primary objective of toxicological testing is to determine the effects of chemicals on biological systems and to obtain data on the dose-response relations of the chemicals. These data may provide information on the degree of hazard to man and the environment associated with a potential exposure related to a specific use of this chemical. The major difference among toxicity tests is the dose employed and the length of exposure to the chemical agent. The term

dose

is used to specify the amount of chemical administered, usually expressed per unit body weight.

Effect