ABSTRACT
Swine are used extensively in biomedical research with a significant increase in recent decades. They are replacing other mammalian species such as the dog as animal models, while also being developed as a model on their own merit. Swine have become accepted as a general surgical model. This increased use of swine in the laboratory would not have occurred if technical procedures for handling, husbandry, and anesthetizing the species were not refined during the same time period.
