ABSTRACT

There have been extensive publications on the rheology of hyaluronic acid (HA), many of which take a complicated, theoretical approach to the subject.

The goal of this chapter, however, is to put in perspective some basic concepts of the rheology critical to the understanding of the biophysical property of HA and its derivatives, while reducing the mathematical formula and calculations to the minimum. The study of the structure-property relationship has always been an essential part of the basic science for any biomaterial, and for HA, the property that stands out is its viscosity.