ABSTRACT

In this second edition of Signals and Systems Analysis in Biomedical Engineering, the author has preserved and updated Chapters 1 through 10, dealing with the powerful mathematical tools of linear systems analysis applied to physiological and biochemical systems. Chapter 7 deals with joint time-frequency (JTF) analysis of linear, time-variant (nonstationary) systems and emphasizes the utility of this method in the description and analysis of nonstationary biomedical signals. Chapter 8 is all about noise, how to describe it, and how it propagates through linear and nonlinear systems. Chapter 8 also describes signal averaging, the lock-in amplier, and data “scrubbing,” and introduces the application of statistics to genomic systems. In Chapter 9, physiological systems (PSs) are considered as examples of nonstationary nonlinear systems, and analysis of PSs are reviewed by describing function analysis and Gaussian noise-based techniques.