ABSTRACT

In its most general form, a DNA array is usually a substrate (nylon membrane, glass or plastic) on which one deposits single-stranded DNAs (ssDNA)with various sequences. Usually, the ssDNA is printed in localized features that are arranged in a regular grid-like pattern. In this book, we will conform with the nomenclature proposed by Duggan et al. [139], and we will refer to the ssDNA printed on the solid substrate as a probe.