ABSTRACT

Randomized clinical trials have become the gold standard for modern medical research. Randomization, in the context of a trial with a treatment and a control, is defined as “a process by which all participants are equally likely to be assigned to either the intervention or control group” (Friedman, Furberg, and DeMets 1998, p. 43). Randomization can remove the potential of bias, and also provides a basis to guarantee the validity of statistical tests at the conclusion of the trial.