ABSTRACT
The natural world, both terrestrial and marine, is a varied and bountiful source for new drugs. Yet until recently only natural products from terrestrial sources have been developed into, or have formed the basis for, modern medicines. The advent of more sophisticated and efœcient means to
12.1 Introduction .......................................................................................................................... 291 12.2 Ecteinascidin-743 (Yondelis) ................................................................................................292
