ABSTRACT
FIGURE 19.1 Activated carboxymethyl dextran for SPR. Carboxymethyl dextran is activated with carbodiimide/NHS to form the succinimide derivative of the carboxymethyl group which can be coupled with amine groups (see Johnsson, B., Löfås, S., and Lindquist, G., Immobilization of proteins to a carboxymethyldextran-modi ed gold surface for biospeci c interaction analysis in SPR sensors, Anal. Biochem. 198, 268-277, 1991; Johnsson, B., Löfås, S., Lindquist, G. et al., Comparison of methods for immobilization to carboxymethyl dextran sensor surfaces by analysis of the speci c activity of monoclonal antibodies, J. Mol. Recognit. 8, 125-131, 1995).
