ABSTRACT

Halogenated aromatic hydrocarbons (HAHs), such as polychlorinated dibenzo-pdioxins (PCDDs), biphenyls (PCBs), and dibenzofurans (PCDFs) and related com­ pounds represent a diverse group of widespread environmental contaminants. PCDD and PCDF formation has been demonstrated to occur as a result of chlorine bleaching of wood pulp; during synthesis of various organochlorine products (such as the her­ bicide 2,4,5-T); during municipal, hospital, and industrial waste incineration; during

metal production and fossil fuel or wood burning as well as from a variety of other sources (1,2). PCBs, on the other hand, were produced commercially for use in trans­ formers, capacitors, heat transfer and hydraulic fluids, and other applications. It has been estimated that greater than 1.5 million metric tons of PCBs have been produced worldwide, with 20%-30% of this amount in the environment (1,3). HAHs represent a class of environmental chemicals that, because of their ubiquitous distribution, toxi­ city, fat solubility, resistance to biological and chemical degradation, and potential for bioaccumulation and biomagnification, can persist for long periods of time and thus could have a significant impact on the health and well-being of humans and animals (2, 3).