ABSTRACT

The advent of non-invasive human brain imaging technologies provided the opportunity for direct examination of the human brain. This occurred about 15 years ago with the related expectation that we were at the threshold of a revolution in our understanding of chronic pain. This expectation remains largely unfullled, although much has been published in the topic. Here we concentrate mainly on our own work in the topic, arguing in general that the subject of brain mechanisms of chronic pain remains in its infancy mainly because of a heavy emphasis in the eld on studying nociception rather than chronicity of pain.