ABSTRACT

The standard primary treatment of women with endometrial adenocarcinoma is total abdominal hysterectomy with bilateral salpingo-oophorectomy. Radiation therapy has also been successfully used in patients with significant co-morbidities that preclude surgery. These options are acceptable in women who are postmenopausal or who do not wish to retain their childbearing potential. Neither radiation therapy nor surgery would be an attractive option for patients who wish to later become pregnant. Primary hormonal therapy has been studied as a means to preserve fertility or to treat patients with

major co-morbidities. This chapter offers a review of the literature of conservative management on endometrial carcinoma with particular emphasis on the premenopausal patient in whom preservation of fertility is desired.