DNA Oxidative Damage
The amount of work dedicated to the study of DNA oxidative damage is large enough to
successfully compete with the studies on lipid peroxidation (Chapters 25 and 26). DNA
molecule is an easy target for the attack of many oxidants including free radicals, transition
metal ions, and active oxygen and nitrogen species. On the other hand, specific effective
repairing mechanisms protect nucleic acids from oxidative damage. This chapter is dedicated
to the consideration of mechanisms of free radical damage and repairing DNA.