ABSTRACT
INTRODUCTION The administration of topical medications to wound sites in the course of wound care is one of the most documented areas of medical history. This chapter, now updated with advancements achieved in the past 10 years, examines many of the popular wound treatments, most of which stem from folk law rather than true science, and provides a summary of the more recently popular growth factors that are emerging for topical use in chronic or difficult wounds. Beyond the topical agents examined in this chapter, there is also a huge range of agents such as phenytoin, botanical extracts, raw honey, enzymes, minerals, and animal proteins that have been investigated for their effects on wound healing that may warrant more attention in further updates.
